… We assessed whether alternative rescreening strategies for persons who receive a negative
… We evaluated 5 rescreening strategies for persons with a negative colonoscopy result at …

… exist at the former end, as they provide an ‘average’ result for … 1000 persons in a hypothetical
cohort of 50-year-olds who had a … , there were two important findings. The first finding is that …

… of screening, re-screening every year until there is an abnormal FIT, timely colonoscopy
follow-… Microsimulation models synthesize existing evidence about the natural history of disease …

… was done only for patients with a negative FOBT result. If … For those start and stop ages, we
first selected the colonoscopy … We used 2 independent microsimulation models to evaluate …

… All persons with an abnormal noncolonoscopy screening test result were assumed to undergo
follow-up colonoscopy. … developed microsimulation models: Simulation Model of CRC (…

… this trial to validate 3 microsimulation models for CRC to long… those who screened positive
being referred to colonoscopy … the screened group, resulting in overestimation of screening …

… the utility of 10-year re-screening with colonoscopy, we used … colonoscopy until the
development of CRC (primary outcome)… , a microsimulation modeling study found that re-screening …

… for first-time screening and rescreening. Each box represents one … The POHEM is a “microsimulation
tool developed by … , all people with positive FOBTs receive colonoscopies. In our …

… a person with a positive FOBT, sigmoidoscopy, or stool DNA test result would be referred for
follow-up colonoscopy … With microsimulation, we mean that each individual in the population …

… rate and the outcome of the test (positive or negative), … rates of 75% for colonoscopy after a
positive result on fecal occult … The higher costs per life-year saved compared with those in our …